Overview
PepLynx is a piece of software for identifying crosslinked spectra from
peptides digested in H
218O. It relies on the
Hardklör
package for identifying crosslinked spectra, then compares the deisotoped
spectra against a protein database.
Publication
Zelter A, Hoopmann MR, Vernon R, Baker D, MacCoss MJ, Davis TN.
Isotope Signatures Allow Identification of Chemically Cross-Linked
Peptides by Mass Spectrometry: A Novel Method to Determine Interresidue
Distances in Protein Structures through Cross-Linking.
J Proteome Res.
(2010) 9(7), pp 3583–3589